The clinical relevance of mycotoxins under realistic airborne exposure levels is not fully established. Most of the evidence that supports health effects is based on case studies rather than controlled studies; studies that have not yet been reproduced or involve symptoms that are subjective. In large epidemiologic studies, general symptoms have been associated with moisture damaged and moldy buildings. Many reported symptoms are subjective and difficult to determine. Results show that the association is general, and mold is not the only possible cause of the symptoms. In any case, indoor mold growth is unacceptable from the perspectives of potential adverse health effects and building performance.

There is a lack of information on specific human responses to well-defined exposures to molds contaminants. There isn’t a proven method to record the type or amount of mold that a person is exposed to, and common symptoms associated with molds exposure are non-specific. Molds are everywhere in the environment and responses to exposure vary widely among individuals. There are no accepted standards for molds sampling in indoor environments or for analyzing and interpreting the data. Most studies are based primarily on baseline environmental data rather than on human dose-response data. Neither OSHA, NIOSH, nor EPA has set the standard for molds exposure.